We team up with expert specialist from diverse fields e.g. OB/GYN, Paediatrics, Haematology, Cardiology, Oncology, etc. to best advice our patients on genetic testing, interpretation of test results and incorporation of the currently available genetic knowledge and know-how to improve the overall quality of medical services provided.

Genetics laboratory
"My son just turned 7. While he was playing football the other day, he fell over and hurt his knee. We took him to the hospital but it was practically impossible to stop the bleeding. Our doctor said he might have haemophilia and asked for testing. What is this -haemophilia? What will happen to my son?"

Come to us and we will help. Haemophilia is a hereditary disorder characterised by an impairment of the blood clotting mechanism of the body, caused by a single gene. We can run all available tests for this gene and communicate to you the disease and its possible consequences.

Genetic counselling
"My dad is diagnosed as Thalassemia carrier. Me and my cousin have fallen in love when we were kids and recently decided to get married. We are aware that this is a consanguineous marriage. Nevertheless, we want to have children. We are afraid that our children will have Thalassemia, too."

Come to us and we will help. Thalassemia is a hereditary disorder. Genetic counselling provides you with the most recent, objective and detailed information on any hereditary disease that you and your partner may carry, as well as the potential risks of transmitting these to your children. It enlightens you on preventive measures against disease risk. It also presents guidance and options on methods available to establish a healthy pregnancy and having healthy children.

Clinical genetics
"Our daughter is 4 years old but she is underdeveloped. She vomits all the time after feeding, has partial sight loss and has difficulties grasping objects with her hands. We have been to numerous doctors but no one seems to know exactly what is wrong with her - and people talk about how advanced medicine is today. How come then they could not solve this problem?"

Come to us and we will help. Diagnosis of rare disorders is a rather meticulous and complex procedure. Clinical genetic services include obtaining the family history, establishing the pedigree and performing physical examination supported with genetic screening when necessary. We shall be there with you after diagnosis on possible treatment options and preventive measures as well.

Pharmacogenetics
"I am a heart patient. At the same time I have high blood pressure and diabetes. I am taking at least 5 pills a day. Lately, I feel extremely tired, my whole body aches, moving my arms and my legs is a nuisance. It's as if I am completely drained. I think these medicines are no good for me!"

Come to us and we will help. Pharmacogenetics is a relatively new scientific discipline that is mainly involved with the interactions between the medications we take, their effect on us and the response we will develop according to our genetic make-up. Together with your specialist, we can develop a customised therapy specific to you and your genes, formulising medications of proper dosage, effectiveness and minimised side effects.

Cancer genetics
"I have been diagnosed with Leukaemia last week. However the doctors have told me that they have not yet identified the exact type and that this may delay effective treatment. I have heard that these tests could be performed somewhere abroad. Yet I don't know where to go or who to consult..."

Come to us and we will help. Leukaemia is a type of blood marrow cancer and has various types. Some of these are rarely seen and exact diagnosis may take longer. Cancer genetic testing aids in differentiating between the subtypes and ascertaining diagnosis. Most of these tests are performed in our laboratories. Besides, if necessary, we can also guide you to one of our international partners who are specialised in specific cancers and give you support throughout the process.

Hereditary cancer counselling
"My mum was diagnosed with breast cancer when she was 50. My grand-aunt passed away due to this malady as well. Will I also get cancer?"

Come to us and we will help. Hereditary cancer counselling helps reveal your genetic predisposition to the disease upon obtaining your detailed family history, physical examination, backed up with genetic screening when necessary. It provides information on preventive measures including life-style and nutritional habit changes.

Teratogenicity counselling
"Today I found out that I am 6 weeks pregnant. I was not expecting this so I am a bit surprised but very happy. However I have some worries now. I had taken pain relievers and antibiotic last week due to an infected tooth. Could I have hurt my baby? And what am I going to do the next time I have pain? My doctor says we need to be extremely cautious about teratogenicity. How would I know?"

Come to us and we will help. Teratogenicity is a science dealing with the capacity of a drug to cause fetal malformations. Although beneficial for the mother's health, certain drugs impose a risk of birth defects for the baby. Especially certain preparations are highly risky at certain stages of a pregnancy. For correct dosage, effectiveness and minimised side effects, together with your specialist, we can develop a customised therapy and correct drug regime before, throughout and after your pregnancy.

All our clinical genetics and genetic counselling activities dealing with reproductive health, mother, father and child health and IVF matters before, during and after establishment of a healthy pregnancy are offered as our Healthy Generations Counselling service. PGD "We have been longing years long for a healthy child. We have tried IVF as well but I had three consequent miscarriages. My doctor says our chances might be higher if we go for PGD. What is it, this PGD?" Come to us and we will help. Pre-implantation Genetic Diagnosis (PGD) is genetic screening procedure allowing diagnosis of genetic malformations and/or disorders prior to establishment of the pregnancy thus allowing only the transfer of healthy embryos to the mother. We will perform all related tests in our state-of-the-art laboratories and our specialist will give you information and support throughout the whole process. When is PGD indicative? Consequent miscarriages More than 2 unexplainable unsuccessful IVF cycles Unexplainable infertility " Advanced maternal age Male related sterility Previous cases of pregnancy to or birth of child with genetic disorder Chromosomal aberrations in family history X-transmitted disease in family history Hereditary disease diagnosis in one or both of the parents Consanguineous marriages Necessity to have a healthy baby with HLA profile matching to existing brother or sister(s). Our services Pre-PGD clinical genetics and counselling PGD clinical genetics and counselling Family health clinical genetics and counselling Child health clinical genetics and counselling For more information and your appointment please call us. At NESILLERGENETIK, no genetic testing is performed prior to providing complete and unbiased information and obtaining an official informed consent form from our patients. Dr. Gulay Ozgon (MD, PhD) Medical Genetics, Clinical Pharmacology gulay.ozgon@nesiller.com

Our laboratories and our experts are also actively engaged in R&D activities in regard to scientific improvement, population health and improving the quality of healthcare services delivered. We are particularly interested in identification and validation of biomarkers for chronic complex diseases (CCD) and cancer with diagnostic (early detection, drug response monitoring) and therapeutic potential. We have submitted a number of research projects both at national and international levels. Our platform also offers its scientific and technical partnership in your research activities.